Riveting, audacious and now more urgent than ever in this vast update, The Emperor of All Maladies is a masterpiece. The story of cancer is a human one - a tale of chance discoveries, seized opportunities and human endurance. From innovative early surgeries to the Curies' ultimately tragic work with radiation; from Sidney Farber's hugely risky discovery of chemotherapy to the author's treatment of his own patients, The Emperor of All Maladies is a profound and revelatory portrait of an enigmatic disease humans have lived with, and perished from, for more than five thousand years. In this updated edition of Siddhartha Mukherjee's instant classic, four new chapters reveal what has changed in the universe of cancer in the years since the book was first published. With moving eloquence, he offers an insight into our evolving understanding of cancer's causes and the emerging, revolutionary new treatments that might shape its future, including those that Mukherjee himself has helped devise.