Seventy-year-old avant-garde composer Peter Els opens the door one evening to find the police on his doorstep. His home microbiology lab - where he is conducting the latest experiment in his lifelong attempt to find musical patterns in surprising places - has aroused the suspicions of Homeland Security. Panicked by the raid, Els turns fugitive, earning him the moniker 'Bioterrorist Bach'. He hatches a daring plan to transform this disastrous collision with the security state into an unforgettable work of art that will reawaken its audience to the sounds all around it. A gripping escape narrative filled with lyrical wonder, Orfeo is both a portrait of a creative, obsessive man, and a reflection on finding melodies in everyday life.