University systems need visionary leadership like never before. Public university systems—state-wide networks of universities—educate over 75 percent of public four-year college students. These systems have a tremendous impact on research, workforce development, and the overall economic and civic health of their states. In Leading Multi-Campus University Systems, editors Nancy Zimpher, Rebecca Martin, and Jessica Todtman explore the transformative potential of public university systems to drive equity, innovation, and community prosperity. Written by experienced system leaders, this book profiles twelve dynamic executives who have reshaped multi-campus systems to meet today's challenges. Drawing on extensive interviews, case studies, and primary sources, contributors uncover the unique qualities and strategies that define effective system leadership. From tackling equity gaps and outdated structures to responding to crises with bold action, these leaders exemplify "systemness"—leveraging collective strength to achieve greater impact. These higher education leaders realized the power of systems through a multitude of strategies—such as funding realignment, structural change, professional development, and policy redesigns—to ensure affordable access, meaningful and high-quality learning opportunities, and equitable outcomes for all students. Through vivid narratives and actionable insights, this book redefines the role of higher education systems in addressing societal needs and offers invaluable guidance for leaders navigating the complexities of multi-campus organizations in an era of immense change.